Histone Acetyltransferase Inhibitor II – CAS 932749-62-7 – Calbiochem

Descrição detalhada : A cell-permeable bis-arylidene cyclohexanone compound that acts as a p300/CBP-selective histone acetyltransferase inhibitor (IC50 = 5 µM), while it affects GCN5 and PCAF only at much higher concentrations (30% and 0% inhibition, respectively, at 5 µM inhibitor concentration). Shown to decrease histone H3 acetylation (IC50 <=40 µM) and induce chromatin condensation in HeLa cells., A cell-permeable bis-arylidene cyclohexanone compound that acts as a p300/CBP-selective histone acetyltransferase inhibitor (IC50 = 5 µM), while it affects GCN5 and PCAF only at much higher concentrations (30% and 0% inhibition, respectively, at 5 µM inhibitor concentration). Shown to decrease histone H3 acetylation (IC50 <= 40 µM) and induce chromatin condensation in HeLa cells.
Sinónimos : Histone Acetyltransferase Inhibitor II - CAS 932749-62-7 - Calbiochem; 2,6- bis-(3-Bromo-4-hydroxybenzylidene)cyclohexanone, HAT Inhibitor II, p300/CBP Inhibitor II, GCN5 Inhibitor I; 2,6-bis-(3-Bromo-4-hydroxybenzylidene)cyclohexanone, HAT Inhibitor II, p300/CBP Inhibitor II, GCN5 Inhibitor I
Fórmula molecula r: C20H16Br2O3
Armazenamento : 2-8C; 2-8C; 2-8C
Embalagem : 1X10MG