IL-6, Human Recombinant Animal Free

Descrição detalhada : Product Source: Protein is expressed in E.coli.The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided., IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals throughthe IL-6 receptor system that consists of two chains, IL-6R and gp130. Murine IL-6 is inactive on human cells, while bothhuman and murine are equally active on murine cells. Recombinant human IL-6 is a 20.9 kDa protein containing 184 amino acid residues.
Sinónimos : Interleukin-6, IL6
Armazenamento : -20°C
Embalagem : 1X1EA