Indomethacin – CAS 53-86-1 – Calbiochem

Descrição detalhada : A cell-permeable, non-steroidal anti-inflammatory, anti-pyretic agent. Non-selective cyclooxygenase (COX) inhibitor (IC50 = 740 nM for COX-1; IC50 = 970 nM for COX-2). Inhibits phospholipase A2 (IC50 = 145 µM). Reported to reduce Abeta42 levels independently of COX activity., A non-steroidal anti-inflammatory, cell permeable, antipyretic agent. Non-selective COX inhibitor (IC50 = 740 nM for COX-1; IC50 = 970 nM for COX-2). Inhibits phospholipase A2 (IC50 = 145 µM). Strongly inhibits insoluble transthyretin (TTR) amyloid fibril formation and suppresses production of Abeta-peptide and secreted form of APP by inhibition of APP mRNA levels in NG108-15 cells.
Sinónimos : Indomethacin - CAS 53-86-1 - Calbiochem; 1-( p-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acid; 1-(p-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acid
Fórmula molecula r: C19H16ClNO4
Armazenamento : 10-30C
Embalagem : 1X10GM