InSolution Akt Inhibitor IV – Calbiochem

REF : 124015-1MG
Marca : Sigma-Aldrich
Descrição :InSolution Akt Inhibitor IV - Calbiochem The InSolution Akt Inhibitor IV controls the biological activity of Akt. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
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Descrição detalhada : A cell-permeable benzimidazole compound that inhibits Akt phosphorylation/activation presumably by targeting the ATP binding site of a kinase upstream of Akt, but downstream of PI3K. Shown to block Akt-mediated FOXO1a nuclear export (IC50 = 625 nM) and cell proliferation (IC50<1.25 microM) in 786-O cells. Unlike phosphatidylinositol analog-based Akt inhibitors (Cat. Nos. 124005, 124008, 124009), this inhibitor does not affect PI3K.
Sinónimos : InSolution Akt Inhibitor IV - Calbiochem
Fórmula molecula r: C31H27IN4S
Armazenamento : 2-8C; 2-8C; 2-8C; 2-8C
Embalagem : 1X1MG