InSolution Aphidicolin – CAS 38966-21-1 – Calbiochem

Descrição detalhada : A cell-permeable tetracyclic diterpene antibiotic. Cell synchronization agent. Blocks the cell cycle at the early S-phase. Specific, non-competitive and reversible inhibitor of DNA polymerase alpha and delta in eukaryotic cells and in some viruses of animal origin. Potentiates apoptosis induced by arabinosyl nucleosides in leukemia cell lines. Also induces apoptosis in HeLaS3 cells, but inhibits vincristine (>Cat. No. 677181)-induced apoptosis in the p53-negative human prostate cancer cell line PC-3.
Sinónimos : InSolution Aphidicolin - CAS 38966-21-1 - Calbiochem
Fórmula molecula r: C20H34O4
Armazenamento : -70C
Embalagem : 1X1EA