InSolution Casein Kinase II Inhibitor I – Calbiochem

REF : 218708-5MG
Marca : Sigma-Aldrich
Descrição :InSolution Casein Kinase II Inhibitor I - Calbiochem The InSolution Casein Kinase II Inhibitor I controls the biological activity of Casein Kinase II. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
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Descrição detalhada : A cell-permeable, highly selective, ATP/GTP-competitive casein kinase II (CKII) inhibitor (IC50 = 900 nM and 1.6 µM for rat liver and human recombinant CKII, respectively) and DYRK (IC50<1 µM for DYRK1a). Specificity for CKII has been reported following the screening of 33 kinases, including PKA, Akt, PKC, MKK1, ERK2, p38, JNK, Lck, Lyn, and Syk. Also reported to inhibit NS3-associated viral helicase activity in hepatitis C virus (HCV) (IC50 = 20 and 60 µM using DNA and RNA substrates, respectively) and West Nile virus (WNV) (IC50 = 1.7 µM and 900 nM using DNA and RNA substrates, respectively).
Sinónimos : InSolution Casein Kinase II Inhibitor I - Calbiochem
Fórmula molecula r: C6HBr4N3
Armazenamento : 2-8C; 2-8C; 2-8C; 2-8C
Embalagem : 1X5MG