InSolution Caspase-3 Inhibitor I, Cell-Permeable – Calbiochem

REF : 235427-1MG
Marca : Sigma-Aldrich
Descrição :InSolution Caspase-3 Inhibitor I, Cell-Permeable - Calbiochem The InSolution Caspase-3 Inhibitor I, Cell-Permeable controls the biological activity of Caspase-3. This small molecule/inhibitor is primarily used for Cancer applications.
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Descrição detalhada : A cell-permeable inhibitor of caspase-3. The C-terminal DEVD-CHO sequence of this peptide is a highly specific, potent, and reversible inhibitor of caspase-3 (Ki<1 nM) that has also been shown to strongly inhibit PARP cleavage in cultured human osteosarcoma cell extracts (IC50 = 200 pM). The N-terminal sequence (residues 1-16) corresponds to the hydrophobic region (h-region) of the signal peptide of Kaposi fibroblast growth factor (K-FGF) and confers cell-permeability to the peptide.
Sinónimos : InSolution Caspase-3 Inhibitor I, Cell-Permeable - Calbiochem; Cell-permeable, DEVD-CHO; CPP32/Apopain Inhibitor, Cell-permeable
Fórmula molecula r: C94H158N20O27
Armazenamento : -20C
Embalagem : 1X1MG