InSolution Cycloheximide – CAS 66-81-9 – Calbiochem

REF : 239765-1ML
Marca : Sigma-Aldrich
Descrição :InSolution Cycloheximide - CAS 66-81-9 - Calbiochem InSolution Cycloheximide, CAS 66-81-9, is a 100 mg/ml, sterile-filtered solution of Cycloheximide (Cat. No. 239763) in DMSO. An antifungal antibiotic that inhibits protein synthesis in eukaryotes.
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Descrição detalhada : A convenient ready-to-use form of Cycloheximide (Cat. No. 239763). An anti-fungal antibiotic that inhibits protein synthesis in eukaryotes but not in prokaryotes. Interacts directly with the translocase enzyme, interfering with the translocation step. Also inhibits cell-free protein synthesis in eukaryotes. Competitively inhibits hFKBP12 (Ki = 3.4 µM). Triggers apoptosis in HL-60 cells, T-cell hybridomas, Burkitt's lymphoma cells, and a variety of other cell types, including rodent macrophages. Induces DNA fragmentation in macrophages, but inhibits DNA cleavage in rat thymocytes treated with thapsigargin, methylprednisolone, and ionomycin. Rapidly destroyed in alkaline solutions.
Sinónimos : InSolution Cycloheximide - CAS 66-81-9 - Calbiochem
Fórmula molecula r: C15H23NO4
Armazenamento : 2-8C; 2-8C; 2-8C
Embalagem : 1X1ML