InSolution IKK Inhibitor VII – CAS 873225-46-8 – Calbiochem

Descrição detalhada : A cell-permeable benzamido-pyrimidine compound that acts as a potent, selective, and ATP-competitive inhibitor of IKK (IC50 = 40, 70, and 200 nM for IKK-2, IKK complex, and IKK-1, respectively). Inhibits cellular IkappaBalpha degradation and NF-kappaB-mediated gene expression in vitro in HUVEC cells and has been shown to exhibit excellent in vivo efficacy both in mice and rats.
Sinónimos : InSolution IKK Inhibitor VII - CAS 873225-46-8 - Calbiochem; (4-(4-(Benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)phenyl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone, InSolution IKK Inhibitor VII, IKK 16; IKK 16, (4-(4-(Benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)phenyl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone, InSolution IKK Inhibitor VII
Fórmula molecula r: C28H29N5OS
Armazenamento : -70C
Embalagem : 1X1EA