InSolution Phorbol-12-myristate-13-acetate – CAS 16561-29-8 – Calbiochem

Descrição detalhada : Most commonly-used phorbol ester. Extremely potent mouse skin tumor promoter. Activates protein kinase C in vivo and in vitro, even at nM concentrations. Promotes the expression of iNOS in cultured hepatocytes. Activates Ca2+-ATPase and potentiates forskolin (>Cat. No. 344270, >Cat. No. 344282)-induced cAMP formation. Inhibits apoptosis induced by the Fas antigen, but induces apoptosis in HL-60 promyelocytic leukemia cells. Its binding is reversible.
Sinónimos : InSolution Phorbol-12-myristate-13-acetate - CAS 16561-29-8 - Calbiochem; 12-O-Tetradecanoyl-phorbol-13-acetate, PMA, TPA
Fórmula molecula r: C36H56O8
Armazenamento : -70C
Embalagem : 1X1EA