InSolution SB 202190 – CAS 152121-30-7 – Calbiochem

Descrição detalhada : A potent and cell-permeable inhibitor of p38 MAP kinase. Inhibits p38 phosphorylation of myelin basic protein (MBP) with no effect on the activity of the ERK or JNK MAP kinase subgroups. Also inhibits the kinase activity of p38beta (IC50 = 350 nM) and p38 phosphorylation of activating transcription factor 2 (ATF-2; IC50 = 280 nM). Blocks LPS-induced TNF-alpha and interleukin biosynthesis. Reported to block LDL expression in Hep52 cells.
Sinónimos : InSolution SB 202190 - CAS 152121-30-7 - Calbiochem; InSolution p38 MAP Kinase Inhibitor II
Fórmula molecula r: C20H14FN3O
Armazenamento : -20C
Embalagem : 1X1ML