InSolution Sirtinol – Calbiochem

Descrição detalhada : A cell-permeable 2-hydroxy-1-napthaldehyde derivative that acts as a specific and a direct inhibitor of sirtuin class of histone deacetylase (HDAC) activity. Does not affect human HDAC1. Reported to block Sir2p transcriptional silencing activity in vivo (IC50 = 25 µM) and NAD-dependent HDAC activity in purified recombinant yeast Sir2p and human SIRT2 in vitro (IC50 = 68 µM and 38 µM, respectively).
Sinónimos : InSolution Sirtinol - Calbiochem; 2-[(2-Hydroxynaphthalen-1-ylmethylene)amino]-N-(1-phenethyl)benzamide, Sir Two Inhibitor Naphthol, SIRT1 Inhibitor I, SIRT1/2 Inhibitor I, SIRT2 Inhibitor III
Fórmula molecula r: C26H22N2O2
Armazenamento : 2-8C; 2-8C; 2-8C; 2-8C
Embalagem : 1X1MG