InSolution STAT3 Inhibitor VI, S3I-201 – Calbiochem

REF : 573130-5MG
Marca : Sigma-Aldrich
Descrição :InSolution STAT3 Inhibitor VI, S3I-201 - Calbiochem The InSolution STAT3 Inhibitor VI, S3I-201, also referenced under CAS 501919-59-1, controls the biological activity of STAT3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
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Descrição detalhada : A cell-permeable amidosalicylic acid compound that binds Stat3-SH2 domain and prevents Stat3 phosphorylation/activation, dimerization, DNA-binding, and Stat3-dependent transcription. Shown to arrest Stat3-dependent tumor growth both in cultures in vitro (effective conc. ≤100 microM) and in a murine xenograft model in vivo (5 mg/kg, i.v.). The solid form of this compound (Cat. No. 573102) is also available., A cell-permeable amidosalicylic acid compound that binds Stat3-SH2 domain and prevents Stat3 phosphorylation/activation, dimerization, DNA-binding, and Stat3-dependent transcription. Shown to arrest Stat3-dependent tumor growth both in cultures in vitro (effective conc. ≤100 microM) and in a murine xenograft model in vivo (5 mg/kg, i.v.).
Sinónimos : InSolution STAT3 Inhibitor VI, S3I-201 - Calbiochem
Fórmula molecula r: C16H15NO7S
Armazenamento : -20C
Embalagem : 1X5MG