InSolution Staurosporine, Streptomyces sp.

REF : 569396-100UG
Marca : Sigma-Aldrich
Descrição :InSolution Staurosporine, Streptomyces sp. InSolution Staurosporine, Streptomyces sp. CAS 62996-74-1, is provided as a 1 mM (100 µg/214 µl) solution of Staurosporine (Cat. No. 569397) in DMSO
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Descrição detalhada : A potent, cell-permeable broad spectrum inhibitor of protein kinases. Inhibits CaM kinase (IC50 = 20 nM), myosin light chain kinase (IC50 = 1.3 nM), protein kinase A (IC50 = 7 nM), protein kinase C (IC50 = 0.7 nM), and protein kinase G (IC50 = 8.5 nM). Also inhibits platelet aggregation induced by collagen or ADP but has no effect on thrombin-induced platelet aggregation. Induces apoptosis in human malignant glioma cell lines. Arrests normal cells at the G1 checkpoint.
Sinónimos : InSolution Staurosporine, Streptomyces sp.; PKA Inhibitor II, MLCK Inhibitor I
Fórmula molecula r: C28H26N4O3
Armazenamento : -70C
Embalagem : 1X100UG