InSolution TGF-beta RI Kinase Inhibitor II, RepSox – CAS 446859-33-2 – Calbiochem

Descrição detalhada : A cell-permeable, potent, selective, reversible, and ATP-competitive inhibitor of TGF-beta type I receptor (ALK5; IC50 = 23 nM, 4 nM and 18 nM for ALK5 binding, ALK5 auto-phosphorylation, and TGF-beta cellular assay in HepG2 cells, respectively). Minimally affects a panel of 9 closely related kinases including p38 MAPK (IC50 >16 µM).
Sinónimos : InSolution TGF-beta RI Kinase Inhibitor II, RepSox - CAS 446859-33-2 - Calbiochem; RepSox InSolution, E-616452 InSolution, ALK5 Inhibitor II, Transforming Growth Factor-beta, Type I Receptor Kinase Inhibitor II, 2-(3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine
Fórmula molecula r: C17H13N5
Armazenamento : -70C
Embalagem : 1X1EA