JAK2 Inhibitor IV – CAS 1110502-30-1 – Calbiochem
REF : 420139-5MG
Marca : Sigma-Aldrich
Descrição :JAK2 Inhibitor IV - CAS 1110502-30-1 - Calbiochem The JAK2 Inhibitor IV, also referenced under CAS 1110502-30-1, controls the biological activity of JAK2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
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Categoria : Small Molecules
Descrição detalhada : An aminoindazole compound that potently inhibits the activity of both the wild-type JAK2 and the constitutively active V617F mutant (IC50 = 78 and 206 nM, respectively) frequently found in patients with clonal polycythemia vera, essential thrombocytosis, and chronic idiopathic myelofibrosis, while exhibiting much reduced activity against JAK3 (IC50 = 2.93 µM).
Sinónimos : JAK2 Inhibitor IV - CAS 1110502-30-1 - Calbiochem; 3-Amino-5-(N- tert-butylsulfonamido-4-phenyl)-indazole
Fórmula molecula r: C17H20N4O2S
Armazenamento : 2-8C; 2-8C; 2-8C
Embalagem : 1X5MG
Sinónimos : JAK2 Inhibitor IV - CAS 1110502-30-1 - Calbiochem; 3-Amino-5-(N- tert-butylsulfonamido-4-phenyl)-indazole
Fórmula molecula r: C17H20N4O2S
Armazenamento : 2-8C; 2-8C; 2-8C
Embalagem : 1X5MG