JAK3 Inhibitor I – CAS 202475-60-3 – Calbiochem

REF : 420101-5MG
Marca : Sigma-Aldrich
Descrição :JAK3 Inhibitor I - CAS 202475-60-3 - Calbiochem The JAK3 Inhibitor I, also referenced under CAS 202475-60-3, controls the biological activity of JAK3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
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Descrição detalhada : A cell-permeable, reversible, potent, ATP-competitive, and specific inhibitor of JAK3 (Janus family kinase 3) (IC50 = 78 µM). Has no effect on either JAK1, JAK2, Zap/Syk or Src kinases. Blocks thrombin-induced platelet aggregation., A cell-permeable, reversible, potent, ATP-competitive, and specific inhibitor of JAK3 (Janus family kinase 3; IC50 = 78 µM). Has no effect on JAK1, JAK2, or Zap/Syk or Src tyrosine kinases. Acts as a potent inhibitor of glioblastoma cell adhesion and migration. Also reported to block thrombin-induced platelet aggregation.
Sinónimos : JAK3 Inhibitor I - CAS 202475-60-3 - Calbiochem; 4-(4?-Hydroxyphenyl)amino-6,7-dimethoxyquinazoline, WHI-P131
Fórmula molecula r: C16H15N3O3
Armazenamento : -20C
Embalagem : 1X5MG