JNK Inhibitor VIII – CAS 894804-07-0 – Calbiochem

REF : 420135-5MG
Marca : Sigma-Aldrich
Descrição :JNK Inhibitor VIII - CAS 894804-07-0 - Calbiochem The JNK Inhibitor VIII, also referenced under CAS 894804-07-0, controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
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Descrição detalhada : A cell-permeable pyridinylamide compound that acts as an ATP-competitive, reversible inhibitor of JNK (Ki = 2 nM, 4 nM and 52 nM for JNK1, 2 and 3, respectively) and displays excellent selectivity over 72 other kinases. Inhibits c-jun phosphorylation with an EC50 of 920 nM in HepG2 cells. Preferentially blocks the growth of PTEN null mouse embryonic fibroblasts.
Sinónimos : JNK Inhibitor VIII - CAS 894804-07-0 - Calbiochem; N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-(2,5-dimethoxyphenyl)acetamide
Fórmula molecula r: C18H20N4O4
Armazenamento : -20C
Embalagem : 1X5MG