Lavendustin A – CAS 125697-92-9 – Calbiochem

Descrição detalhada : A cell-permeable, reversible, substrate competitive, and potent inhibitor of EGF receptor tyrosine kinase (IC50 = 11 nM) and pp60c-src (IC50 = 500 nM) with little effect on protein kinase A or protein kinase C (IC50 >200 µM). Also inhibits NMDA-stimulated cGMP production (IC50 = 30 nM). Exhibits anti-proliferative properties. Suppresses the angiogenic action of vascular endothelial growth factor in rats., A cell-permeable, reversible, and substrate competitive inhibitor of EGF receptor tyrosine kinase (IC50 = 11 nM) and p60c-src (IC50 = 500 nM) with little effect on protein kinase A or protein kinase C (IC50 >200 µM). Also inhibits NMDA-stimulated cGMP production (IC50 = 30 nM). Exhibits anti-proliferative properties. Suppresses the angiogenic action of vascular endothelial growth factor (VEGF) in rats.
Sinónimos : Lavendustin A - CAS 125697-92-9 - Calbiochem; 5-Amino-[(N-2,5-dihydroxybenzyl)-N?-2-hydroxybenzyl]salicylic Acid, RG14355
Fórmula molecula r: C21H19NO6
Armazenamento : -20C
Embalagem : 1X1MG