Leptomycin B solution from Streptomyces sp.

REF : L2913-.5UG
Marca : Sigma-Aldrich
Descrição :Leptomycin B solution from Streptomyces sp. >=95% (HPLC), Supplied in methanol: water (7:3)
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Descrição detalhada : Leptomycin B is an anti-fungal antibiotic, anti-tumor cytotoxin that inhibits CRM1-dependent, NES-dependent nucleo-cytoplasmic translocation (nuclear export inhibitor). NES containing proteins include HIV-1 REV; actin, c-Abl, cyclin B1, MDM2/p53, I?B, MPF, PKA and MEK.
Sinónimos : Antibiotic CI 940; Elactocin; LMB; Mantuamycin
Fórmula molecula r: C33H48O6
Armazenamento : -20C
Embalagem : 1X.5UG