Milli-Mark(R) Anti-CD41-FITC Antibody, clone 5B12

Descrição detalhada : CD41 is the alpha-subunit of the CD41/CD61 complex (GPIIb-IIIa), a calcium-dependent, non-covalently associated heterodimer. CD41 is a 135 kDa molecule, consisting of 2 peptides: a 120 kDa alpha chain and a 23 kDa beta chain. The alpha chain and the beta chain are linked by a single disulphide bond. The alpha chain contains four calcium-binding sites and is entirely extracellular, while the beta-chain has extracellular, transmembrane, and cytoplasmic domains (Sun, 1997). The CD41/CD61 complex appears early in megakaryocyte maturation (Vinci, 1984). Anti-CD41, 5B12, was included in the Fifth International Workshop and Conference on Human Leukocyte Differentiation Antigens and studies by a number of laboratories confirmed its reactivity with CD41 (Honda, 1995).
Sinónimos : Integrin alpha-IIb, Platelet membrane glycoprotein IIb, GPalpha IIb, GPIIb
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA