MMP-2/MMP-3 Inhibitor III, PD166793 – CAS 199850-67-4 – Calbiochem

REF : 444284-5MG
Marca : Sigma-Aldrich
Descrição :MMP-2/MMP-3 Inhibitor III, PD166793 - CAS 199850-67-4 - Calbiochem The MMP-2/MMP-3 Inhibitor III, PD166793, also referenced under CAS 199850-67-4, controls the biological activity of MMP-2/MMP-3. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
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Descrição detalhada : A cell-permeable biphenylsulfonylvaline compound that acts as a potent inhibitor against MMP-2, -3, and -13 (IC50 = 47, 12, and 8 nM, respectively) and a weaker inhibitor against AMP deaminase (20% inhibition at 0.1 µM), MMP-1, -7, -9, and -14 (IC50 = 6.1, 7.2, 7.9, and 0.24 µM, respectively). Shown to offer therapeutic benefits in vivo in various animal models of heart failure and diabetes.
Sinónimos : MMP-2/MMP-3 Inhibitor III, PD166793 - CAS 199850-67-4 - Calbiochem; (S)-2-(4?-Bromo-biphenyl-4-sulfonylamino-3-methylbutyric acid)
Fórmula molecula r: C17H18BrNO4S
Armazenamento : 2-8C; 2-8C; 2-8C
Embalagem : 1X5MG