Monoclonal Anti-Calcineurin (beta-Subunit) antibody produced in mouse

Descrição detalhada : Calcineurin (CaN, heterodimeric enzyme) is a Ca(2+)/calmodulin (CaM)-stimulated protein phosphatase 3 (PPP3) consisting of a catalytic A subunit (CnA) and a Ca(2+)-binding regulatory B subunit (CnB). The calcium-binding regulatory subunit (calcineurin B) is coded by the PPP3R1 gene located on human chromosome 2. Protein phosphatase 3, regulatory subunit B, ? (PPP3R1) is also known as CALN, CCN1, CNA1, CALNA, PPP2B and CALNA1. The regulatory subunit (calcineurin B) is widely expressed in brain while the catalytic subunit (calcineurin A) is abundantly expressed in Hassall?s corpuscles, localized in the thymic medulla and represents the terminal stages of thymic medullary epithelium., Monoclonal Anti-Calcineurin (beta-subunit) (mouse IgM isotype) is derived from the CN-B1 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with purified bovine brain calcineurin preparation. Two different calcineurin B has been reported in rat testis.
Sinónimos : Anti-CALNB1; Anti-CNB; Anti-CNB1
Armazenamento : -20C
Embalagem : 1X.2ML