Monoclonal Anti-Na+/K+ ATPase (alpha1 Subunit) antibody produced in mouse

REF : A275-100UL
Marca : Sigma-Aldrich
Descrição :Monoclonal Anti-Na+/K+ ATPase (alpha1 Subunit) antibody produced in mouse clone 9A-5, ascites fluid
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Descrição detalhada : The gene coding Na+,K+-ATPase is mapped to human chromosome 1p13.1, which is a plasma membrane ion transporter. It is ubiquitously expressed in all animals. The ? subunit of the protein consists of 10 transmembrane helices, and three cytoplasmic domains A, N and P that serve as actuator, in nucleotide-binding and for phosphorylation, respectively., Epitope mapping studies indicate the antibody binds within the intracellular region at or near Asp-369 of the alpha subunit. Staining is consistent with the plasma membrane localization of Na+/K+ ATPase., Mouse Monoclonal Anti-Na+/K+ ATPase (alpha1 Subunit) antibody localizes the Na+/ K+ ATPase alpha1 subunit in human, canine, rat and avian tissues., Na+/K+ transporting ATPase subunit alpha1 is an ion transport pump critical for maintaining the gradient of Na and K ions across the plasma membrane.
Armazenamento : -20C
Embalagem : 1X100UL