Neurogenesis Inducer V, KHS101 – Calbiochem

Descrição detalhada : A blood brain barrier permeable pyrimidinyl-aminothiazole compound that specifically interacts with TACC3 (transforming acidic coiledcoil-containing protein 3) and promotes nuclear localization of ARNT2 (aryl-hydrocarbon receptor nuclear translocator 2). Shown to significantly induce neuronal differentiation of cultured rat hippocampal NPCs (neural progenitor cells; EC50 ~ 1 µM) and in adult rats (6 mg/kg, s.c.) and suppress proliferation.
Sinónimos : Neurogenesis Inducer V, KHS101 - Calbiochem; N?-Isobutyl-N²-((2-phenylthiazol-4-yl)methyl)pyrimidine-2,4-diamine
Fórmula molecula r: C18H21N5S
Armazenamento : 2-8C; 2-8C; 2-8C
Embalagem : 1X10MG