Nomega-Hydroxy-nor-L-arginine, Diacetate Salt – CAS 189302-40-7 – Calbiochem

Descrição detalhada : A potent, selective, competitive, and high affinity inhibitor of arginase. Shown to inhibit arginase from rat liver (IC50 = 2 µM) and mouse macrophages (IC50 = 50 µM). Specifically interacts with the manganese-cluster of the enzyme active site. Does not act as a substrate or as an inhibitor of NOS. Hence, it may serve as a useful tool to study the interplays between arginase and NOS., A potent, selective, competitive, and high affinity inhibitor of arginase. Shown to inhibit arginase from rat liver (IC50 = 2 µM) and mouse macrophages (IC50 = 50 µM). Shown to specifically interact with the manganese-cluster of the enzyme active site. Does not function as a substrate or as an inhibitor for NOS. Hence, nor-NOHA may be a useful tool to study the interplays between arginase and NOS.
Sinónimos : Nomega-Hydroxy-nor-L-arginine, Diacetate Salt - CAS 189302-40-7 - Calbiochem; nor-NOHA, 2CH?CO?H, L-2-Amino-(4-(2?-hydroxyguanidino)butyric Acid, 2CH?CO?H
Fórmula molecula r: C5H12N4O3 · 2C2H4O2
Armazenamento : -20C
Embalagem : 1X1MG