PAC-1

Descrição detalhada : Procaspase-activating compound 1 (PAC-1) is an ortho-hydroxy N-acyl hydrazine compound. It is cytotoxic to a variety of cancer cells, such as lymphoma, leukaemia, breast carcinoma and glioblastoma. High doses of PAC-1 can promote neuroexcitation. It helps in the in vitro autoactivation of the proenzyme protease, which acts as a prototype for other protease activating compounds. PAC-1 dependant activation of procaspase-3 is associated with the chelation of zinc.
Sinónimos : (4-Benzylpiperazino)acetic acid (3-allyl-2-hyroxybenzylidene)hydrazide; 1-Piperazineacetic acid, 2-(phenylmethyl)-,[[2-hydroxy-3-(2-propenyl)phenyl]methylene]hyrrazide
Fórmula molecula r: C23H28N4O2
Armazenamento : room temp
Embalagem : 1X5MG