Pefabloc(R) SC PLUS

Descrição detalhada : Pefabloc SC is a specific, potent, and irreversible inhibitor of serine proteases. The inhibitory activity is comparable to PMSF or DFP, but Pefabloc SC is nontoxic to cells. The Pefabloc SC PLUS set combines the serine protease inhibitor Pefabloc SC with a uniquely formulated Pefabloc SC protector (PSC-Protector), adding additional convenience and reliability to the safe, stable protease inhibition provided by Pefabloc SC.Recent findings indicate that sulfonyl-type serine protease inhibitors such as Pefabloc SC and PMSF can bind covalently to proteins. This can occur when the inhibitors are used in high concentrations, or during extended incubation times under alkaline conditions. This interaction adversely affects the tyrosine and lysine residues of a protein, as well as the free amino terminus. The PLUS additive (PSC-Protector) included with this set prevents covalent attachment of Pefabloc SC to proteins when used in higher concentrations and extended incubation times at an alkaline pH.
Sinónimos : pefabloc; serine protease inhibitor
Armazenamento : 2-8C
Embalagem : 1X1EA