Pertussis Toxin, Bordetella pertussis – CAS 70323-44-3 – Calbiochem

Descrição detalhada : NOTE: This product is not activated, hence for use in cell-free systems, activation is required., A protein endotoxin that catalyzes ADP-ribosylation of guanine nucleotide-binding regulatory proteins Gi, Go, and GT. Affects glucose homeostasis, immune cell function, and the induction of leukocytosis. Used in the study of adenylate cyclase regulation and the role of Gi proteins. Holotoxin activity is determined in CHO cell assay. Note: this product is not activated. If used with an intact cell system, the cells will activate the toxin. If used in a cell-free system, activation may be achieved by the methods of either Kaslow, H.R., and Burns, D.L. 1992. and Moss, J. 1983., This Pertussis toxin, CAS 70323-44-3, catalyzes ADP-ribosylation of guanine nucleotide-binding regulatory proteins Gi, Go, and Gt., Obtain a uniform suspension before use. A protein endotoxin that catalyzes ADP-ribosylation of guanine nucleotide-binding regulatory proteins Gi, Go, and Gt. Used in the study of adenylate cyclase regulation and the role of Gi proteins. Holotoxin activity is determined in a CHO cell assay.
Sinónimos : Pertussis Toxin, Bordetella pertussis - CAS 70323-44-3 - Calbiochem
Armazenamento : 2-8C; 2-8C
Embalagem : 1X50UG