Platelet Membrane Glycoproteins, IIbIIIa, Human Platelets

REF : 528240-1MG
Marca : Sigma-Aldrich
Categoria :
Descrição detalhada : Native, platelet membrane glycoprotein IIbIIIaA from human platelets. A platelet integrin that binds fibrinogen via the recognition sequence Arg-Gly-Asp-Ser. Acts as a receptor for such adhesive ligands as fibrinogen, fibronectin and von Willebrand factor during platelet stimulation. Glycoproteins IIb and IIIa constitute the fibrinogen receptor and are required for platelet aggregation. Glycoprotein IIb consists of two disulfide-linked subunits, GPIIbalpha and GPIIbbeta, whereas GPIIIa has only one polypeptide chain., Native, platelet membrane glycoprotein IIbIIIaA from human platelets. A platelet integrin that binds to fibrinogen via the recognition sequence Arg-Gly-Asp-Ser. Acts as a receptor for such adhesive ligands as fibrinogen, fibronectin and von Willebrand factor during platelet stimulation. Glycoproteins IIb and IIIa constitute the fibrinogen receptor and are required for platelet aggregation. Glycoprotein IIb consists of two disulfide-linked subunits, GPIIbalpha and GPIIbbeta, whereas GPIIIa has only one polypeptide chain.
Sinónimos : GPIIbIIIa, Fibrinogen Receptor, CD41/CD61
Armazenamento : -70C
Embalagem : 1X1MG