PMA

Descrição detalhada : PMA (Phorbol 12-myristate 13-acetate) is an activator of protein kinase C (PKC) and a known tumor promoting agent. PMA also exhibits clastogenic (chromosome-breaking) activity. , Phorbol 12-myristate 13-acetate (PMA) can induce the activity of PLD1 (phospholipase D1) but not PLD2 (phospholipase D2).Through the protein kinase C (PKC) signaling pathway, PMA is a tumor promoter associated with:. gene transcription. cell growth. cell differentiation. programmed cell death. immune pathway. receptor desensitizationPhorbol 12-myristate 13-acetate is used to study:. growth factors. hormones. cytokines-mediated regulation of cellular growth and differentiation
Sinónimos : Phorbol 12-myristate 13-acetate; NF-kappaB Activator; PKC Activator; croton oil; phorbol ester; protein kinase C activator; 12-O-Tetradecanoylphorbol 13-acetate; 4beta,9alpha,12beta,13alpha,20-Pentahydroxytiglia-1,6-dien-3-one 12-tetradecanoate 13-acetate; PMA; TPA
Fórmula molecula r: C36H56O8
Armazenamento : -20C
Embalagem : 1X25MG