PON1 Activator, ZNPA – Calbiochem

REF : 529505-10MG
Marca : Sigma-Aldrich
Descrição :PON1 Activator, ZNPA - Calbiochem The PON1 Activator, ZNPA modulates the biological activity of PON1. This small molecule/inhibitor is primarily used for Biochemicals applications.
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Descrição detalhada : A cell-permeable stilbene derivative that serves as an aryl hydrocarbon receptor (AhR) ligand and acts as a highly specific and potent inducer of paraoxonase 1 (PON1). Shown to be a better activator of PON1 mRNA (EC50 = 1 microM) and inducer of PON1 enzymatic activity (>3 fold at 5 microM) when compared to resveratrol (Cat. No. 554325). However, it is devoid of any activity against estrogen receptors and is not shown to inhibit activity of tyrosine kinases. Also shown to antagonize the effects of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) on cytochrome P450 1A1 (CYP1A1).
Sinónimos : PON1 Activator, ZNPA - Calbiochem; (Z)-2,3-bis (4-nitrophenyl)-acrylonitrile
Fórmula molecula r: C15H9N3O4
Armazenamento : -20C
Embalagem : 1X10MG