PTP1B Inhibitor – CAS 765317-72-4 – Calbiochem

REF : 539741-5MG
Marca : Sigma-Aldrich
Descrição :PTP1B Inhibitor - CAS 765317-72-4 - Calbiochem PTP1B Inhibitor, CAS 765317-72-4, is a cell-permeable, selective, reversible and non-competitive allosteric inhibitor of PTP1B (IC?? = 4 µM and 8 µM for PTP1B403 and PTP1B298, respectively).
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Descrição detalhada : A cell-permeable, selective, reversible, and non-competitive allosteric inhibitor of PTP1B (IC50 = 4 µM and 8 µM for PTP1B403 and PTP1B298, respectively). Binds to a novel site away from the catalytic pocket and inhibits PTP1B activity by preventing closure of the WPD loop. Also available in InSolution format (Cat. No. 539749.
Sinónimos : PTP1B Inhibitor - CAS 765317-72-4 - Calbiochem; 3-(3,5-Dibromo-4-hydroxy-benzoyl)-2-ethyl-benzofuran-6-sulfonicacid-(4-(thiazol-2-ylsulfamyl)-phenyl)-amide, PTP Inhibitor XXII
Fórmula molecula r: C26H19Br2N3O7S3
Armazenamento : -20C
Embalagem : 1X5MG