RIPAb+ PUM2 Antibody

Descrição detalhada : RIPAb+ antibodies are evaluated using the RNA Binding Protein Immunoprecipitation (RIP) assay. Each RIPAb+ antibody set includes a negative control antibody to ensure specificity of the RIP reaction and is verified for the co-immunoprecipitation of RNA associated specifically with the immunoprecipitated RNA-binding protein of interest. Where appropriate, the RIPAb+ set also includes quantitative RT-PCR control primers (RIP Primers) to biologically validate your IP results by successfully co-precipitating the specific RNA targets, such as messenger RNAs. The qPCR protocol and primer sequences are provided, allowing researchers to validate RIP protocols when using the antibody in their experimental context. If a target specific assay is not provided, the RIPAb+ kit is validated using an automated microfluidics-based assay by enrichment of detectable RNA over control immunoprecipitation.PUM2 is a sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding to the 3'-UTR of mRNA targets. The PUM class of proteins plays an active role in the sustainability of mitotic stem cell proliferation and the regulation of cell development and differentiation.
Sinónimos : pumilio homolog 2 (Drosophila), pumilio homolog 2, pumilio (Drosphila) homolog 2
Armazenamento : -20°C
Embalagem : 1X1EA