Ro-32-0432 – CAS 145333-02-4 – Calbiochem

Descrição detalhada : A selective cell-permeable protein kinase C inhibitor. Displays about a 10-fold greater selectivity for PKCalpha (IC50 = 9 nM) and a 4-fold greater selectivity for PKCbetaI (IC50 = 28 nM) over PKCepsilon (IC50 = 108 nM). Also prevents T-cell driven chronic inflammatory responses in vivo., A selective cell-permeable protein kinase C inhibitor. Displays about 10-fold greater selectivity for PKCalpha (IC50 = 9 nM) and 4-fold greater selectivity for PKCbetaI (IC50 = 28 nM) over PKCepsilon (IC50 = 108 nM). Also prevents T cell-driven chronic inflammatory responses in vivo.Please note that the molecular weight for this compound is batch-specific due to variable water content.
Sinónimos : Ro-32-0432 - CAS 145333-02-4 - Calbiochem; 2-{8-[(Dimethylamino)methyl]-6,7,8,9-tetrahydropyrido[1,2-a]indol-3-yl}-3-(1-methyl-1H-indol-3-yl)maleimide, HCl, Bisindolylmaleimide XI, HCl, 3-(8-((dimethylamino)methyl)-6,7,8,9-tetrahydropyrido[1,2- a]indol-10-y1)-4-(1-methyl-1 H-indol-3
Fórmula molecula r: C28H28N4O2 · xHCl
Armazenamento : 2-8C; 2-8C; 2-8C
Embalagem : 1X1MG