Rolipram – CAS 61413-54-5 – Calbiochem

Descrição detalhada : Cell permeable, selective competitive inhibitor of cAMP-specific phosphodiesterase IV (IC50 = 800 nM). Rolipram does not inhibit PDE I or PDE II, even at concentrations as high as 100 µM. It is only a weak inhibitor of PDE III (IC50 = 100 µM). A rolipram-insensitive phosphodiesterase IV subtype is also known to exist., A cell-permeable, selective inhibitor of cAMP-specific phosphodiesterase (PDE IV; IC50 = 800 nM). A rolipram-insensitive PDE IV subtype is also known to exist. Also inhibits NF-kappaB and NFAT activation in Jurkat and primary T cells.
Sinónimos : Rolipram - CAS 61413-54-5 - Calbiochem; 4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone
Fórmula molecula r: C16H21NO3
Armazenamento : 2-8C; 2-8C
Embalagem : 1X5MG