SILu(TM)Prot CCL2 C-C motif chemokine 2 human

Descrição detalhada : CCL2, the most thoroughly characterized CC chemokine, is a monocyte-specific chemoattractant that was demonstrated to attract T lymphocytes and NK cells, but not neutrophils. Enhanced expression of CCL2 was demonstrated in a variety of pathologic conditions, associated with inflammation and mononuclear cell infiltration. Extensive experimental evidence suggests that CCL2 is highly expressed in atherosclerotic plaques. In a recent study, CCL2 was shown to have value as a biomarker for risk stratification in both the initial and the chronic phases after an acute coronary syndromes (ACS). In contrast to CRP, CCL2 levels may be an indicator of long-term cardiovascular risk rather than a marker of acute prognosis. In urine, CCL2 levels were directly associated to Systemic Lupus Erythematosus disease activity, making it a non-invasive biomarker (avoiding blood sampling or tissue biopsies).
Sinónimos : HC11; Monocyte chemoattractant protein 1; Monocyte chemotactic protein 1(MCP-1); Monocyte secretory protein JE; Monocytechemoattractantprotein1; Monocytechemotacticandactivatingfactor(MCAF); Small-inducible cytokine A2
Armazenamento : -20C
Embalagem : 1X10UG