SMC(R) Human TDP-43 Immunoassay Kit

Descrição detalhada : The human Transactive Response DNA-binding Protein 43 (TDP-43) is a transcriptional repressor which can bind to both DNA and RNA, and regulate functions such as mRNA splicing, microRNA biogenesis, and transcription. While this 414 amino acid long protein can be found in a variety of tissue types, it is most frequently studied in the context of neuroscience research, as misfolding, phosphorylation, and aggregation of TDP-43 in neurons can has been observed in a variety of neurodegenerative disorders, including frontotemporal dementia (FTL), amyotrophic lateral sclerosis (ALS), and certain subsets of Alzheimer's disease patients. To empower research to evaluate TDP-43 as a cognitive biomarker in both healthy and disease states such as ALS and FTL, the new SMC(R) Human TDP-43 High Sensitivity Immunoassay Kit scientists can measure this analyte in CSF, serum, and plasma samples even at low abundance.Research Category:NeuroscienceneurologicalResearch Sub-Category:Alzheimer's DiseaseAgingNervous SystemNeurodegenerative DiseasesNeurofilament & Neuron MetabolismNeuronal & Glial MarkersNeuroregenerative MedicineNeuroscienceTechnique(s)SMC(R) : High sensitivity protein biomarker detection immunoassay
Sinónimos : TDP-43 Single Molecule Counting kit; TDP-43 immunoassay kit; TDP-43 ultra-sensitive immunoassay; Transactive Response DNA-binding Protein 43 immunoassay kit
Armazenamento : 2-8C