sRANKL human

Descrição detalhada : TRANCE (TNF-related activation-induced cytokine), also known as sRANKL (soluble receptor activator of nuclear factor K-B ligand), is encoded by the gene mapped to human chromosome 13q14.11. sRANKL and RANK (receptor activator of nuclear factors-KB) are members of the tumor necrosis factor (TNF) superfamily of ligands and receptors that play an important role in the regulation of specific immunity and bone turnover. RANKL is expressed in a variety of cells including osteoblasts, fibroblasts, activated T-cells and bone marrow stromal cells. Recombinant human sRANKL is a 20kDa polypeptide comprising the TNF homologous region of RANKL (176 amino acid residues).
Sinónimos : ODF (Osteoclast differentiation factor); TNFSF11; TRANCE (TNF-related activation-induced cytokine); soluble Receptor Activator of NFkB Ligand
Armazenamento : -20C
Embalagem : 1X10UG