STAT3 Inhibitor VI, S3I-201 – CAS 501919-59-1 – Calbiochem

Descrição detalhada : A cell-permeable amidosalicylic acid compound that binds Stat3-SH2 domain and prevents Stat3 phosphorylation/activation, dimerization, DNA-binding, and Stat3-dependent transcription. Shown to arrest Stat3-dependent tumor growth both in cultures in vitro (effective conc. ≤100 microM) and in a murine xenograft model in vivo (5 mg/kg, i.v.). Also available as a 50 mM solution in DMSO (Cat. No. 573130).
Sinónimos : STAT3 Inhibitor VI, S3I-201 - CAS 501919-59-1 - Calbiochem; 2-Hydroxy-4-(((4-methylphenyl)sulfonyloxy)acetyl)amino)-benzoic acid, NSC 74859
Fórmula molecula r: C16H15NO7S
Armazenamento : -20C
Embalagem : 1X25MG