STAT5 Inhibitor II, IQDMA – Calbiochem

REF : 420294-10MG
Marca : Sigma-Aldrich
Descrição :STAT5 Inhibitor II, IQDMA - Calbiochem The STAT5 Inhibitor II, IQDMA controls the biological activity of STAT5.
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Descrição detalhada : A cell-permeable indoloquinoline compound that exhibits anticancer activity and inhibits the growth of A549 lung cancer cells (IC50 = 8 µM), as well as HL-60 (IC50 = 5 µM) and K562 (IC50 = 8 µM) leukemia cells. IQDMA-mediated apoptosis is shown to correlate with a downregulation of STAT5 pathway signaling in HL-60 and K562 cultures, while JNK and p38 signalings are shown to be activated in A549 cells upon IQDMA treatment.
Sinónimos : STAT5 Inhibitor II, IQDMA - Calbiochem; N1-(11H-indolo[3,2-c]quinolin-6-yl)-N2,N2-dimethylethane-1,2-diamine
Fórmula molecula r: C19H20N4
Armazenamento : 2-8C; 2-8C
Embalagem : 1X10MG