sTRAIL Receptor-1 (DR4) human

REF : SRP3164-50UG

Marca : Sigma-Aldrich

Descrição :sTRAIL Receptor-1 (DR4) human recombinant, expressed in E. coli, >=98% (SDS-PAGE), >=98% (HPLC), suitable for cell culture
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Categoria : Cell Signaling

Descrição detalhada : Soluble tumor necrosis factor-related apoptosis-inducing ligand-receptor 1 (sTRAIL-R1) also known as DR4, is encoded by the gene mapped to human chromosome 8p21-22. Recombinant human soluble TRAIL Receptor-1/DR4 is a 22.7kDa protein (216 amino acid residues) consisting of the TNFR homologous, cysteine rich portion of the extracellular domain. TRAIL Receptor-1/DR4 and TRAIL Receptor-2/DR5 belong to the TNFR superfamily of transmembrane proteins. TRAIL-R1 contains a cytoplasmic "death domain," which can activate the cell's apoptotic machinery. TRAIL Receptor-1/DR4 is activated by binding to either membrane anchored or soluble TRAIL/Apo2L.
Sinónimos : Apo2; DR4; TNFRSF10A; soluble TRAIL Receptor-1
Armazenamento : -20C
Embalagem : 1X50UG