Sumanirole Maleate – CAS 179386-44-8 – Calbiochem

Descrição detalhada : An extremely selective dopamine D2 receptor agonist (Ki = 9 nM). Commonly used in Parkinson's Disease models and to reproduce cocaine's discriminative stimulus effects. Sumanirole has greater than 200-fold selectivity for the D2 receptor subtype versus the other dopamine receptor subtypes in radioligand binding assays. In cell-based assays, sumanirole is a fully efficacious agonist, with EC50 values between 17 and 75 nM. In animals, sumanirole elicits many physiological responses attributed to D2-like receptor function.
Sinónimos : Sumanirole Maleate - CAS 179386-44-8 - Calbiochem; Dopamine D? receptor Agonist, Sumanirole, PNU 95666, PNU95666
Fórmula molecula r: C11H13N3O · xC4H4O4
Armazenamento : -20C
Embalagem : 1X1EA