TPEN – CAS 16858-02-9 – Calbiochem

Descrição detalhada : Lipid-soluble heavy metal chelator that crosses artificial and natural membranes. Auxiliary reagent in certain techniques used for measuring free Ca2+ levels in cells. Also useful in extracting Abeta amyloid deposits from Alzheimer's disease brain tissue. Has extremely high affinity for heavy metals but low affinity for Ca2+ and Mg2+. Induces DNA fragmentation when chelated with Zn2+ and induces apoptosis in thymocytes. Strips heavy metals from liposome-trapped QUIN 2 (Cat. No. 551826)., Lipid-soluble heavy metal chelator that crosses artificial and natural membranes. Auxiliary reagent in certain techniques used for measuring free Ca2+ in cells. Has an extremely high affinity for heavy metals but a low affinity for Ca2+ and Mg2+. Induces DNA fragmentation when chelated with Zn2+ and causes apoptosis in thymocytes. Strips heavy metals from liposome-trapped QUIN 2. Shown to be useful in extracting Abeta depostis from Alzheimer's disease brain tissue.
Sinónimos : TPEN - CAS 16858-02-9 - Calbiochem; N,N,N?,N?- tetrakis-(2-Pyridylmethyl)ethylenediamine
Fórmula molecula r: C26H28N6
Armazenamento : 15-25C
Embalagem : 1X100MG