Tubulin Polymerization Inhibitor II
REF : 654164-5MG
Marca : Sigma-Aldrich
Descrição :Tubulin Polymerization Inhibitor II The Tubulin Polymerization Inhibitor II, also referenced under CAS 1151995-69-5, acts as an effective anti-microtubule agent. This small molecule/inhibitor is primarily used for Cell Structure applications.
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Categoria : Small Molecules
Descrição detalhada : A cell-permeable, SU5416- (Cat. Nos. 676487 and 676498) derived combretastatin A-4 (Cat. No. 234200) analog that acts as an effective anti-microtubule agent (IC50 = 4.5 µM in inhibiting polymerization of purified porcine brain tubulin) and displays extremely potent anti-proliferative activity towards various cancer cell lines (GI50<10 nM for 46 lines among a 53 NCI panel tested).
Sinónimos : Tubulin Polymerization Inhibitor II; (E)-1,3-Dihydro-6-methoxy-3-(3,4,5-trimethoxybenzylidene)-1H-indol-2-one
Fórmula molecula r: C19H19NO5
Armazenamento : 2-8C; 2-8C; 2-8C
Embalagem : 1X5MG
Sinónimos : Tubulin Polymerization Inhibitor II; (E)-1,3-Dihydro-6-methoxy-3-(3,4,5-trimethoxybenzylidene)-1H-indol-2-one
Fórmula molecula r: C19H19NO5
Armazenamento : 2-8C; 2-8C; 2-8C
Embalagem : 1X5MG