Vitamin D₃, 1alpha, 25-Dihydroxy- – CAS 32222-06-3 – Calbiochem

Descrição detalhada : Active hormonal form of vitamin D, formed by the renal 1-hydroxylation of 25-(OH)D3. Has immunomodulatory properties in vitro and in vivo. Prevents the development of clinical diabetes in NOD mice, which are an animal model of human autoimmune diabetes. Induces reversible hydrolysis of the sphingomyelin cycle and generates ceramide. Stimulates intestinal Ca2+ and phosphate transport and mobilizes Ca2+ from bone. Involved in cellular differentiation, carcinogenesis, and insulin secretion., Has immunomodulatory properties in vitro and in vivo. Prevents the development of clinical diabetes in NOD mice, an animal model of human autoimmune diabetes. Regulates c-myc transcription. Induces reversible hydrolysis of sphingomyelin cycle and generates ceramide. Stimulates intestinal Ca2+ and phosphate transport and mobilizes Ca2+ from bone. Also available as a 1 mM solution in DMSO (Cat. No. 509721).
Sinónimos : Vitamin D?, 1alpha, 25-Dihydroxy- - CAS 32222-06-3 - Calbiochem; 1,25-(OH)?-D?, Calcitriol
Fórmula molecula r: C27H44O3
Armazenamento : -70C
Embalagem : 1X50UG