Vitronectin, Human Purified Protein

REF : CC080
Marca : Sigma-Aldrich
Descrição detalhada : Vitronectin (S-protein) is a multi-functional plasma and extracellular matrix protein with defined activity in cell adhesion, thrombosis, complement activation, fibrinolysis, inflammation, and platelet adhesion. Vitronectin binds to other macromolecules and participates in regulatory circuits to control these processes. Some target macromolecules that interact with vitronectin are heparin, PAI-1, proteases such as thrombin and urokinase-type plasminogen activator (uPA), serine protease inhibitor-protease complexes, the uPA receptor, and a sub-class of integrin receptors on the surface of cells. Vitronectin is also applied as a thin coating on tissue-culture surfaces, which is useful to promote cell attachment, spreading, proliferation, and differentiation of many normal and neoplastic cells, and to study cell migration., Product Source: Human plasma; tested negative for antibodies to HBsAg and HIV., PROPERTIES: Binds to heparin. Active in cell attachment of MG63 cells.
Sinónimos : S-protein
Armazenamento : -70C
Embalagem : 1X1EA