Wnt Antagonist II, IWP-2 – CAS 686770-61-6 – Calbiochem

REF : 681671-10MG
Marca : Sigma-Aldrich
Descrição :Wnt Antagonist II, IWP-2 - CAS 686770-61-6 - Calbiochem The Wnt Antagonist II, IWP-2, also referenced under CAS 686770-61-6, controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for Cancer applications.
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Descrição detalhada : A cell-permeable benzothiazolyl-acetamide compound that inhibits the cellular Wnt processing and secretion via selective blockage of MBOAT (membrane-bound O-acyltranferase) family member Porcn- (Porcupine) mediated Wnt palmitoylation. IWP-2 does not affect Wnt/beta-catenin signaling pathway in general and, unlike IWR-1-endo (Cat. No. 681669), displays no effect against Wnt-stimulated cellular responses., A cell-permeable benzothiazolyl-acetamide compound that inhibits the cellular Wnt processing and secretion via selective blockage of MBOAT (membrane-bound O-acyltranferase) family member Porcn- (Porcupine) mediated Wnt palmitoylation. IWP-2 does not affect Wnt/beta-catenin signaling pathway in general and, unlike IWR-1-endo (Cat. No. 681669), displays no effect against Wnt-stimulated cellular responses. Also available as a 10 mM solution in DMSO (Cat. No. 506072).
Sinónimos : Wnt Antagonist II, IWP-2 - CAS 686770-61-6 - Calbiochem; Inhibitor of Wnt Production-2, Wnt Pathway Inhibitor II, Porcn Inhibitor I; Inhibitor of Wnt Production-2, Wnt Pathway Inhibitor II, Porcn Inhibitor I
Fórmula molecula r: C22H18N4O2S3
Armazenamento : 2-8C; 2-8C; 2-8C
Embalagem : 1X10MG