InSolution Akt Inhibitor V, Triciribine – CAS 35943-35-2 – Calbiochem

REF : 124038-2MG
Marca : Sigma-Aldrich
Descrição :InSolution Akt Inhibitor V, Triciribine - CAS 35943-35-2 - Calbiochem The InSolution Akt Inhibitor V, Triciribine, also referenced under CAS 35943-35-2, controls the biological activity of Akt. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
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Descrição detalhada : A cell-permeable and reversible tricyclic nucleoside that selectively inhibits the cellular phosphorylation/activation of Akt1/2/3 by targeting an Akt effector molecule other than PI 3-K or PDK. Exhibits little effect towards cellular signaling pathways mediated by PKC, PKA, SGK, Stat3, p38, ERK1/2, or JNK. Shown to preferentially induce apoptosis and growth arrest in cancer cells with aberrant Akt activity both in vitro (≥60% in cell proliferation at 20 microM) and in vivo (≥80% inhibition in tumor growth in mice at 1 mg/kg/day, i.p.).
Sinónimos : InSolution Akt Inhibitor V, Triciribine - CAS 35943-35-2 - Calbiochem
Fórmula molecula r: C13H16N6O4
Armazenamento : -70C
Embalagem : 1X2MG