Autophagy Inhibitor, 3-MA – CAS 5142-23-4 – Calbiochem

Descrição detalhada : A widely used cell-permeable autophagic sequestration blocker that effectly protects cerebellar granule cells from apoptosis following serum/potassium deprivation. Although a known class III PI3K inhibitor (IC50 = 4.5 mM in cell-free enzymatic assays), 3-MA exhibits quite distinct pharmacological properties from those of two other PI3K inhibitors, LY 294002 (Cat. Nos. 440202 and 440204) and Wortmannin (Cat. No. 681675), A widely used cell-permeable autophagic sequestration blocker that effectly protects cerebellar granule cells from apoptosis following serum/potassium deprivation. Although a known class III PI3K inhibitor (IC50 = 4.5 mM in cell-free enzymatic assays), 3-MA exhibits quite distinct pharmacological properties from those of two other PI3K inhibitors, LY 294002 (Cat. Nos. 440202 and 440204) and Wortmannin (Cat. No. 681675)
Sinónimos : Autophagy Inhibitor, 3-MA - CAS 5142-23-4 - Calbiochem; 3-Methyladenine
Fórmula molecula r: C6H7N5
Armazenamento : 2-8C; 2-8C; 2-8C
Embalagem : 1X50MG